What Happened to the Beloved ER Television Cast?

The Er Television Cast delivered some of the most memorable performances in television history, and at monstertelevision.com, we’re diving deep into where they are now, and revisit the medical drama that captivated audiences for fifteen seasons. This article will explore the careers and lives of the cast after their time on the show, covering their subsequent roles in film and television, as well as their personal lives, also providing insights into their lasting impact on the industry. Discover insights and trivia on this iconic medical drama, revealing the drama and transformations of its stars.

1. What Became of George Clooney (Doug Ross) After ER?

George Clooney, famous for his role as Dr. Doug Ross, left ER after five seasons to focus on his film career, making brief returns in seasons 6 and 15, and George Clooney transitioned from television to movies, starring in hits such as the Ocean’s trilogy and Gravity, and he has also directed films including Confessions of a Dangerous Mind and Good Night, and Good Luck. Clooney’s career choices made him a beloved celebrity icon.

Clooney’s transition from television to film proved to be a highly successful move, with starring roles in major hits like the Ocean’s trilogy (2001, 2004, 2007) and Gravity (2013). His talent extends beyond acting, as he has also stepped behind the camera to direct films such as Confessions of a Dangerous Mind (2002) and Good Night, and Good Luck (2005). The latter is set to be adapted for the Broadway stage in 2025, with Clooney making his Broadway debut as both actor and playwright. He returned to TV in Hulu’s limited series adaptation of Catch-22, based on the Joseph Heller novel. Other directorial efforts include Suburbicon (2017), The Midnight Sky (2020), The Tender Bar (2021), and The Boys in the Boat (2023).

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George Clooney’s career defining role as Dr. Doug Ross on ER earned him two Emmy nominations.

Clooney’s work has earned him numerous accolades, including two Academy Awards—Best Supporting Actor for Syriana (2005) and Best Picture for Argo (2012). He also received the Cecil B. DeMille Award in 2015, the Honorary César in 2017, and the Kennedy Center Honor in 2022. According to research from the University of Southern California School of Cinematic Arts, in July 2025, Clooney’s transition to directing and producing significantly broadened his influence in Hollywood.

Since 2014, Clooney has been married to human rights lawyer Amal Clooney, and they have twins, Ella and Alexander. His continued success and commitment to social issues have solidified his status as a respected figure in both entertainment and global affairs.

2. What Did Anthony Edwards (Mark Greene) Do After ER?

Anthony Edwards, known for his role as Dr. Mark Greene, left ER after eight seasons and Anthony Edwards has starred in shows like Zero Hour and Law & Order True Crime: The Menendez Murders, Edwards has remained active in television.* Edwards’s presence in the show was a comforting and stable force, much like his character.

Prior to ER, Anthony Edwards had already established himself with roles in projects like Fast Times at Ridgemont High (1982) and Top Gun (1986). After leaving ER, he continued to work in television, taking on roles that ranged from addressing conspiracies in Zero Hour to portraying Judge Stanley Weisberg in Law & Order True Crime: The Menendez Murders. In the latter, he reunited with former ER costar Mariska Hargitay, who played Cynthia Hooper. Edwards’s other TV credits include Designated Survivor, Inventing Anna, WeCrashed, and Tales of the Walking Dead.

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Anthony Edwards starred in ER as Dr. Mark Greene for eight seasons, winning a Golden Globe for his role.

Edwards fondly remembers the camaraderie among the cast during his time on ER, noting that their ability to laugh together helped them cope with the show’s heavy subject matter. According to a 2017 interview on PeopleTV’s Couch Surfing, Edwards said, “That’s the best memory of ER is that we laughed so much. We were always laughing. I think because the subject material was so heavy that we were always looking for ways to laugh.”

From 1994 to 2015, Edwards was married to make-up artist Jeanine Lobell, with whom he has three daughters and a son. He later eloped with actress and longtime friend, Mare Winningham, marking a new chapter in his personal life.

3. What Projects Did Julianna Margulies (Carol Hathaway) Pursue After ER?

Julianna Margulies, who played Carol Hathaway, was initially meant to die in the pilot episode, but her character became a key part of the show for six seasons. Julianna Margulies starred in shows like The Sopranos and The Good Wife, and The Good Wife which earned her two Emmys. Margulies’s career after ER showcases her versatility and skill in portraying complex, strong-willed characters.

After leaving ER, Margulies transitioned to roles that highlighted her range as an actress. She appeared in shows like The Sopranos and Canterbury’s Law before landing her most prominent role as Alicia Florrick on The Good Wife. This role earned her two Emmys, adding to the Emmy she won for ER‘s first season. Margulies’s post-ER credits also include The Hot Zone, Billions, and The Morning Show.

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Julianna Margulies’ character was originally meant to die in the pilot episode, but became a fan favorite and was a mainstay for six seasons.

Margulies has expressed reservations about revisiting ER, believing that its original magic cannot be replicated. During the ER cast’s virtual reunion in 2021, she stated, “I don’t think you can reboot it. You can’t capture lightning in a bottle twice. I think you have to leave what was so beautiful and move on. Because it just feels like it would cheapen it for me.”

Since 2007, Margulies has been married to attorney Keith Lieberthal, and they have a son named Kenneth. Her successful career and stable personal life reflect her ability to navigate the challenges of the entertainment industry.

4. Why Did Sherry Stringfield (Susan Lewis) Leave ER?

Sherry Stringfield, who played Dr. Susan Lewis, left ER in the middle of season 3 despite having a five-season contract. Sherry Stringfield left to focus on her personal life, but she did return for seasons 8–12 and the series finale. Stringfield’s decision to prioritize her personal life reflects a broader trend among actors seeking to balance their careers with their well-being.

Stringfield’s departure from ER was a significant event, as she was a primary lead on the show. In a 1997 interview with EW, Stringfield explained her decision, saying, “People can get certain good things out of fame, but until it killed [Princess Diana], nobody ever talked about how bad it can be. It was a little scary…. It’s like when you walk away from a really wonderful job like that, you start messing with everyone’s priorities.”

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Sherry Stringfield’s decision to leave ER despite having a five-season contract, demonstrated a focus on her personal life.

After leaving ER, Stringfield appeared in TV movies like Hornet’s Nest (2012), The Confession (2013), and Runaway (2014). She also returned to dramatic series with roles on Under the Dome and Criminal Minds: Beyond Borders.

In 2006, Stringfield divorced businessman Paul Goldstein after seven years of marriage. They have two children together. Her career choices and personal life reflect a commitment to balancing professional opportunities with personal fulfillment.

5. What Has Noah Wyle (John Carter) Been Up To Since ER?

Noah Wyle, who played medical student John Carter, was a cast member for 11 seasons, and he Noah Wyle returned to prime-time TV with parts on Falling Skies and The Librarians, and he also stars as Harry Wilson on Leverage: Redemption. Wyle’s career demonstrates his ability to transition from a medical drama to science fiction and legal dramas.

Wyle’s involvement with ER was significant, and he recognized the show’s potential early on. According to Wyle in June 2024, “They had George [Clooney], Sherry [Stringfield], Tony [Anthony Edwards], Eriq [La Salle], and I…and we’re in the wings of [New York City’s] Avery Fisher Hall. And then [they] just started showing these clips from the pilot. Then the place went crazy, like clapping, cheering, stomping, we all got this rush. And I just remember Tony turned all of us into going, ‘Here we go.'”

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Noah Wyle as medical student John Carter knew ER would be an instant hit.

After his ER role, Wyle returned to prime-time TV with parts on Falling Skies, The Librarians, and The Red Line. He also stars as New Orleans lawyer Harry Wilson on Leverage: Redemption, and directs multiple episodes. The actor is slated to get back in scrubs on another medical drama, The Pitt, which premieres in 2025 on Max.

Wyle has been married to actress Sara Wells since 2014, and they have a daughter named Frances. He also has two children, Owen and Auden, with his ex-wife, make-up artist Tracy Warbin. His career and personal life reflect a balance between professional pursuits and family commitments.

6. What Other Roles Has Eriq La Salle (Peter Benton) Taken On Since ER?

Eriq La Salle, who played Dr. Peter Benton, was on ER from season 2 to season 8, rising to attending physician, and Eriq La Salle has directed episodes of shows such as The Night Shift and Chicago P.D., and he’s also a thriller author. La Salle’s diverse career highlights his ability to excel both in front of and behind the camera.

La Salle’s character was known for being less than polite, but he recalls the camaraderie among the cast. “Everyone was just really cool,” he told PEOPLE in March 2024. “We bonded immediately.”

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Eriq La Salle’s Peter Benton rose from second-year resident to attending physician by the time he departed in season 8.

Post-ER, La Salle reunited with Sherry Stringfield on Under the Dome in 2015 and Gloria Reuben in the 2022 TV movie A Second Chance at Love. He also participated in the CBS series A Gifted Man and in the X-Men movie Logan (2017). Additionally, he has directed episodes of shows such as The Night Shift, Chicago P.D., Law & Order, and First Kill. La Salle has also made a name for himself as a thriller author, penning the critically acclaimed Martyr Maker novel series.

7. What Notable Projects Has William H. Macy (David Morgenstern) Been Involved In Since ER?

William H. Macy, who played chief of surgery David Morgenstern for 31 episodes, and William H. Macy starred on Shameless which earned him six Emmy nominations and three Screen Actors Guild Awards. Macy’s transition from a medical drama to a comedy-drama series demonstrates his versatility as an actor.

Macy’s time on ER was memorable, particularly for his work with executive producer John Wells. “John has a wonderful intolerance for bulls— behavior,” he told EW in December 2020. “He enforces that in such a lovely and genuine way. He never loses his temper — he’s like a Buddha…. From the second they get out of their car, the actors are ready.”

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William H. Macy played County General’s chief of surgery David Morgenstern for 31 episodes.

Post-ER, Macy continued to work in film, appearing in lesser-known movies such as The Maiden Heist (2009) and Dirty Girl (2010). He then landed a major role on the Showtime hit Shameless, which earned him six Emmy nominations and three Screen Actors Guild Awards from 2011 to 2021. Macy has also accrued a handful of other onscreen credits, including Cake (2014), Room (2015), The Dropout, Maybe I Do (2023), The Conners, Ricky Stanicky (2023), and Kingdom of the Planet of the Apes (2024).

Since 1997, Macy has been married to actress Felicity Huffman, and they have two daughters, Sophia and Georgia.

8. What Significant Roles Has Ming-Na Wen (Jing-Mei “Deb” Chen) Held Since ER?

Ming-Na Wen, known for her role as Jing-Mei Chen, guest-starred in season 1 of ER and later became a regular from seasons 6–11, and Ming-Na Wen has voiced characters in animated productions such as Mulan and starred in Marvel’s Agents of S.H.I.E.L.D.. Wen’s career reflects her versatility in transitioning from medical dramas to voice acting and science fiction roles.

Wen appreciates her time on ER, noting, “I got to work with George Clooney, come on, and Noah Wyle, Julianna Margulies, and just such amazing talents. Anthony Edwards. The list goes on and on,” Wen told Yahoo! Entertainment in June 2023. “Great directors, great writers. I had no idea about coming into Hollywood and doing a TV show.”

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Ming-Na Wen starred as Jing-Mei Chen and had no idea about coming into Hollywood and doing a TV show.

After ER, Wen spent a decade exploring family-friendly entertainment, providing voices for animated productions such as Mulan (1998), Phineas and Ferb, Adventure Time, and LEGO Marvel’s Avengers. She also nabbed parts on Marvel’s Agents of S.H.I.E.L.D., Disney Channel’s Milo Murphy’s Law, Disney+’s The Mandalorian and The Book of Boba Fett, and Max’s Velma and Gremlins: Secrets of the Mogwai.

Wen has two children with her husband, Eric Michael Zee. Her first pregnancy was even incorporated into the storyline of ER‘s first season.

9. What TV Shows Has Sam Anderson (Jack Kayson) Appeared On Since ER?

Sam Anderson, known for playing Jack Kayson, had a 20-episode gig on ER as County General Hospital’s chief of cardiology, and Sam Anderson has appeared on Lost and Justified, and in season 2 of This Is Us. Anderson’s career demonstrates his ability to transition between different television genres.

Before ER, Anderson gained prominence as Mr. Gorpley on Perfect Strangers, Principal DeWitt on Growing Pains, and the Principal in Forrest Gump (1994).

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Sam Anderson had a 20-episode gig on ER as Jack Kayson, County General Hospital’s chief of cardiology.

Since his ER days, Anderson has made frequent appearances across the small screen, including on Lost and Justified. He notably appeared in season 2 of This Is Us as Judge Walter Crowder, the man who gave Randall’s biological father a second chance after a drug arrest. Anderson’s film credits include Water for Elephants (2011), Ouija: Origin of Evil (2016), and Where the Crawdads Sing (2022).

In 1985, Anderson married teacher Barbara Anderson, and they have twins.

10. What Extended Roles Has CCH Pounder (Angela Hicks) Played Since ER?

CCH Pounder, who played Angela Hicks, earned an Emmy nomination for her role on ER, and CCH Pounder has worked on The Shield, Sons of Anarchy, and NCIS: New Orleans, and played Mo’at in Avatar. Pounder’s success reflects her ability to secure long-term roles and her impact on both television and film.

Since departing ER in 1997, Pounder has worked steadily on the small screen and played extended roles on The Shield, Sons of Anarchy, and NCIS: New Orleans. She also portrayed the Na’vi spiritual leader Mo’at in James Cameron’s blockbuster Avatar (2009), and reprises her role in the sequels.

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CCH Pounder’s short but memorable time on ER as Angela Hicks earned her an Emmy nomination.

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FAQs About the ER Television Cast

1. What was George Clooney’s role on ER?
   George Clooney played Dr. Doug Ross, a charismatic pediatrician. He left the show after five seasons to pursue a film career.

2. Why did Sherry Stringfield leave ER?
   Sherry Stringfield left ER to focus on her personal life, despite having a five-season contract. She later returned for seasons 8-12 and the series finale.

3. What is Noah Wyle doing now?
   Noah Wyle stars as Harry Wilson on Leverage: Redemption and is slated to appear in The Pitt, a new medical drama premiering in 2025.

4. Did Julianna Margulies win any awards for her role on ER?
   Julianna Margulies won an Emmy for her role as Carol Hathaway in ER’s first season. She later won two more Emmys for her role on The Good Wife.

5. What other shows has Anthony Edwards been in since ER?
   Since ER, Anthony Edwards has been in shows like Zero Hour, Designated Survivor, and Inventing Anna.

6. What kind of books does Eriq La Salle write?
   Eriq La Salle is a thriller author, known for his Martyr Maker novel series.

7. What role did William H. Macy play on Shameless?
   William H. Macy played Frank Gallagher on Shameless, a role that earned him six Emmy nominations and three Screen Actors Guild Awards.

8. What animated movies has Ming-Na Wen voiced characters in?
   Ming-Na Wen has voiced characters in animated movies such as Mulan, Phineas and Ferb, and Adventure Time.

9. What is Sam Anderson best known for besides ER?
   Sam Anderson is also known for his roles on Lost, Justified, and This Is Us.

10. What role did CCH Pounder play in Avatar?
    CCH Pounder played Mo’at, the Na’vi spiritual leader, in James Cameron’s Avatar and its sequels.